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Long-term Follow-up of Experimental Exposures to Sarin and Other Anticholinesterase Compounds


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This study is intended to determine whether the group of military personnel (now veterans) experimentally exposed to sarin and other anticholinesterase chemical warfare agents at the Edgewood Arsenal between 1955 and 1975 now suffer any long-term health effects attributable to that exposure. Experimentally exposed subjects and two comparison groups will be surveyed by telephone. This work builds on an earlier follow-up of the Edgewood Arsenal cohort, done by MFUA and the Board on Environmental Studies and Toxicology (BEST) in the early 1980's, but will be a more focused follow-up effort.
The earlier study of long-term health effects was directed toward all experimental subjects, regardless of type of chemical exposure, and was, of necessity, quite general. Limiting further follow-up only to those exposed to sarin and other anticholinesterase (AC) chemical warfare agents permits a more focused investigation. In particular, because it is thought that the actions of AC chemical warfare agents are similar to those of organophosphate pesticides, the study will concentrate on long-term neurologic and neuropsychologic health effects.
Study results will be submitted to a peer-reviewed journal for publication.
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Last Updated: 5/19/2003, 10:43 AM
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